Research & Studies

1. Effectiveness of Supplementary Irrigant Agitation with the Finisher GF Brush on the Debridement of Oval Root Canals Instrumented with the Gentlefile or Nickel Titanium Rotary Instruments

Authors: P. Neelakantan, K. Khan, K. Y. Li, H. Shetty and W. Xi
Institutions: The University of Hong Kong; Nair Hospital Dental College, India; and Sun Yat-sen University, China
Published in: International Endodontic Journal, 2018; 51(7):800–807
DOI: 10.1111/iej.12892
In brief: This ex-vivo study evaluated supplementary irrigant agitation with the Finisher GF Brush in oval root canals and found improved debridement in canals prepared with Gentlefile and size 25/.04 rotary NiTi instruments.

2. Comparison of the Efficacy of Different Techniques for the Removal of Root Canal Filling Material in Artificial Teeth: A Micro-Computed Tomography Study

Authors: Tuan Anh Nguyen, Yaelim Kim, Euiseong Kim, Su-Jung Shin and Sunil Kim
Institutions: Yonsei University College of Dentistry; Yonsei University College of Engineering; and Gangnam Severance Dental Hospital, Seoul, South Korea
Published in: Journal of Clinical Medicine, 2019; 8(7):984
DOI: 10.3390/jcm8070984

In brief: This in-vitro micro-CT study compared conventional retreatment, passive ultrasonic irrigation and supplementary use of the GF Brush in
artificial teeth, and reported the smallest volume of residual root canal filling material in the GF Brush group, particularly in the apical region

3. Activated Irrigation by Gentlefile During Root Canal Therapy

Authors: Agata Koprowicz, Halina Pawlicka and Joanna B. Grącka-Mańkowska
Institution: Department of Endodontics, Medical University of Łódź, Poland
Published in: Journal of Stomatology, 2019; 72(1):34–42
DOI: 10.5114/jos.2019.86495

In brief: This clinical case report presents four root canal treatments in which Gentlefile was used to activate irrigating solutions and discusses its application as an adjunct to mechanical root canal preparation

4. In Vitro Evaluation of Cleaning Effectiveness of EndoActivator vs Tornado Disinfection Kit

Document type: In-vitro laboratory study presentation
Author(s): Not identified in the document
Institution: Microbiological Laboratory, Laniado Hospital, Israel
Publication details: No scientific journal, publication date or DOI is identified in the document.

In brief: This in-vitro laboratory study compared bacterial counts following irrigant activation with the EndoActivator and the Tornado Disinfection Kit in extracted root canals inoculated with Enterococcus faecalis.

5. Cleaning and Shaping Ability of Gentlefile, HyFlex EDM, and ProTaper Next Instruments: A Combined Micro–computed Tomographic and Scanning Electron Microscopic Study

Authors: Pyae Hein Htun, Arata Ebihara, Keiichiro Maki, Shunsuke Kimura, Miki Nishijo and Takashi Okiji
Institution: Tokyo Medical and Dental University (TMDU), Tokyo, Japan
Published in: Journal of Endodontics, 2020; 46(7):973–979
DOI: 10.1016/j.joen.2020.03.027

In brief: This ex-vivo micro-CT and scanning electron microscopy study compared Gentlefile, HyFlex EDM and ProTaper Next in extracted mandibular premolars. Gentlefile demonstrated less mid-root canal transportation than ProTaper Next and better smear-layer removal than both comparison systems.

6. Gentlefile Versus ProTaper in the Shaping Ability in Simulated J-shaped Root Canals

Authors: Xixiong Chen and Jiuyu Ge
Institution: Nanjing University and the Department of Endodontics, Nanjing Stomatological Hospital, Medical School of Nanjing University, Jiangsu, China
Document type: Preprint – not peer reviewed
Published on: Research Square, 8 January 2021
DOI: 10.21203/rs.3.rs-138390/v1

In brief: This laboratory study compared the shaping ability of Gentlefile Red, Gentlefile Blue and ProTaper F2 in simulated J-shaped root canals. Gentlefile produced less canal transportation in the apical and middle regions and demonstrated better centering ability, although two Gentlefile instrument separations were reported.

7. Evaluation of Time to Fracture and Vertical Forces Applied by a Novel Gentlefile System for Root Canal Preparation in Simulated Root Canals

Authors: D. Moreinos, A. Dakar, N. J. Stone and J. Moshonov
Institutions: The Hebrew University–Hadassah School of Dental Medicine and private practice, Jerusalem, Israel
Published in: Journal of Endodontics, 2016;42(3):505–508
DOI: 10.1016/j.joen.2015.12.023

In brief: This laboratory study compared Gentlefile with ProTaper Next and Revo-S and found that Gentlefile required significantly more rotations and a longer time to fracture while applying significantly lower vertical forces to the simulated root canal.

8. Accumulated Hard Tissue Debris and Root Canal Shaping Profiles Following Instrumentation with Gentlefile, One Curve, and Reciproc Blue

Authors: C. W. Chan, V. R. Romeo, A. Lee, C. Zhang, P. Neelakantan and E. Pedullà Institutions: The University of Hong Kong, Hong Kong SAR, China; University of Catania, Italy; and Arthur A. Dugoni School of Dentistry, University of the Pacific, San Francisco, USA Published in: Journal of Endodontics, 2023;49(10):1344–1351 DOI: 10.1016/j.joen.2023.07.019

In brief: This laboratory micro-CT study found that Gentlefile achieved shaping performance comparable with One Curve and Reciproc Blue while potentially removing less dentin and producing less apical transportation, although it required a longer preparation time.

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